Company Filing History:
Years Active: 1999-2008
Title: Cecilia Smith: Innovator in Cell Sample Preparation
Introduction
Cecilia Smith is a notable inventor based in Miami, FL (US). She has made significant contributions to the field of biological research, particularly in the preparation of cell samples for intracellular analysis. With a total of 3 patents to her name, her work has paved the way for advancements in flow cytometry techniques.
Latest Patents
Cecilia's latest patents include a method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry. This innovative method simplifies the conventional sample preparation process by eliminating many steps, making it more suitable for automation. The process involves cell-fixation, permeabilization, and staining of intracellular molecules without any intervening cell-washing steps. The washing step is performed after these processes, utilizing a semi-permeable membrane to filter out interferants while retaining the cells of interest.
Another significant patent is related to ligand-aminodextran-marker conjugates. This invention enhances the detection of target biological materials by providing an improved fluorescent signal. It also describes a method for quantifying multiple populations of cells through the labeling of different pairs of cell populations, each with mutually exclusive cell receptors.
Career Highlights
Cecilia has worked with prominent companies in the field, including Coulter International Corp. and Beckman Coulter, Inc. Her experience in these organizations has contributed to her expertise and innovative capabilities in biological research.
Collaborations
Cecilia has collaborated with notable coworkers such as Olavi Siiman and Patricia Roth, further enriching her professional journey and contributions to the field.
Conclusion
Cecilia Smith's innovative work in cell sample preparation and her contributions to flow cytometry have established her as a significant figure in biological research. Her patents reflect her commitment to advancing scientific techniques and improving methodologies in the field.
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