This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 2024-2025.
Company Filing History:
1 out of 311 
1 out of 3,690 
Years Active: 2024-2025
Title: Cecilia Ramello: Innovator in Cancer Research
Introduction
Cecilia Ramello is a prominent inventor based in Tampa, FL (US). She has made significant contributions to the field of cancer research, particularly in the development of innovative therapies targeting metastatic brain tumors. With a total of 2 patents, her work is paving the way for advancements in cancer treatment.
Latest Patents
Cecilia's latest patents include groundbreaking technologies such as "Metastatic Brain Tumor Targeting Peptides" and "Chimeric Antigen Receptors with Mutated CD28 Phosphorylation Sites." The latter patent discloses chimeric antigen receptor (CAR) polypeptides that can be utilized with adoptive cell transfer to effectively target and eliminate cancers. These CARs comprise a costimulatory signaling region featuring a mutated form of the cytoplasmic domain of CD28, which has altered phosphorylation at Y206 and/or Y218. Additionally, the patents describe immune effector cells, such as T cells or Natural Killer (NK) cells, engineered to express these CARs, thereby providing methods for inducing antitumor immunity in subjects with tumor-associated antigen-expressing cancers.
Career Highlights
Cecilia has worked with esteemed organizations, including the H. Lee Moffitt Cancer Center and Research Institute, Inc. and the United States of America, as represented by the Secretary, Department of Health and Human Services. Her career reflects a strong commitment to advancing cancer research and developing innovative therapeutic strategies.
Collaborations
Cecilia has collaborated with notable colleagues in her field, including Daniel Abate-Daga and James K Liu. These partnerships have contributed to her success and the impact of her research on cancer therapies.
Conclusion
Cecilia Ramello is a trailblazer in cancer research, with her innovative patents and collaborations significantly advancing the field. Her work continues to inspire and pave the way for future breakthroughs in cancer treatment.