Company Filing History:
Years Active: 1992-1994
Title: The Innovative Contributions of Carolyn S. Olson
Introduction
Carolyn S. Olson is a prominent inventor based in Sacramento, CA. She has made significant contributions to the field of diagnostics, particularly in the measurement of bacterial activity and colorimetric reactions. With a total of 2 patents, her work has advanced the understanding and detection of microorganisms in clinical settings.
Latest Patents
One of Carolyn's latest patents is titled "Measurement of bacterial CO.sub.2 production in an isolated fluorophore." This invention features a multi-layer blood culture sensor that includes two matrices. The first matrix is a polymer that is permeable to carbon dioxide and water, but impermeable to protons. A pH-sensitive absorbance-based dye is encapsulated in the polymer. The second matrix contains a pH-insensitive fluorescent dye, which is also encapsulated in a polymer. These matrices are spectrally coupled and are useful for determining microorganisms in a blood culture bottle.
Another notable patent is "Measurement of color reactions by monitoring a change of fluorescence." This process determines the concentration of any substance in a colorimetric, turbidimetric, or nephelometric reaction using a fluorometric detector to measure fluorescence intensity. The method allows for monitoring changes in color by observing the fluorescence intensity of a fluorophore in an inert matrix. The absorption spectrum of the chromophore may overlap with the excitation and/or emission spectrum of the fluorophore, enabling the relationship between fluorescence change and the quantity of the substance of interest.
Career Highlights
Carolyn S. Olson is currently employed at Baxter Diagnostics Inc., where she continues to innovate and contribute to the field of diagnostics. Her work has been instrumental in developing technologies that enhance the accuracy and efficiency of microbial detection.
Collaborations
Throughout her career, Carolyn has collaborated with notable colleagues, including Roger J. Morris and Shoshana Bascomb. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Carolyn S. Olson's contributions to the field of diagnostics through her innovative patents have significantly impacted the detection of microorganisms. Her work exemplifies the importance of research and development in advancing medical technology.