Company Filing History:
Years Active: 2025
Title: Carolyn Pelletier: Innovator in DNA Vector Technology
Introduction
Carolyn Pelletier is a prominent inventor based in Cambridge, MA (US). She has made significant contributions to the field of biotechnology, particularly in the development of DNA vectors. Her innovative work focuses on enhancing the methods of DNA synthesis and vector production.
Latest Patents
Pelletier holds a patent for "Closed-ended DNA vectors obtainable from cell-free synthesis and process for obtaining ceDNA vectors." This patent describes methods for synthetic synthesis and cell-free synthesis of DNA vectors, specifically closed-ended DNA vectors (ceDNA vectors) that have a linear and continuous structure for the delivery and expression of transgenes. The invention relates to an in vitro process for producing closed-ended DNA vectors, along with the corresponding DNA vector products and their applications. The methods outlined in her patent ensure that DNA vectors are free from unwanted side effects due to contaminants that may be introduced during production in cell lines, such as bacterial or insect cell lines.
Career Highlights
Pelletier is currently associated with Generation Bio Co., where she continues to advance her research in DNA technology. Her work is pivotal in developing reliable gene expression methods in vitro, ex vivo, and in vivo using the ceDNA vectors synthesized through her innovative processes.
Collaborations
Some of her notable coworkers include Ozan Alkan and Robert Michael Kotin, who contribute to the collaborative efforts in her research endeavors.
Conclusion
Carolyn Pelletier's contributions to the field of DNA vector technology exemplify her innovative spirit and dedication to advancing biotechnology. Her patent on closed-ended DNA vectors represents a significant step forward in the synthesis and application of DNA vectors, paving the way for future advancements in gene therapy and molecular biology.