Company Filing History:
Years Active: 2025
Title: The Innovations of Caroline Hill
Introduction
Caroline Hill is an accomplished inventor based in Jamaica Plain, MA (US). She has made significant contributions to the field of biotechnology, particularly in the development of long-acting parathyroid hormone peptides. Her innovative work has the potential to greatly impact the treatment of various medical conditions.
Latest Patents
Caroline Hill holds a patent for a long-acting parathyroid hormone peptide (PTH). This invention provides a peptide that is retained in a subject's blood serum for periods that greatly exceed the natural hormone. The long-acting PTH is conjugated to a non-hormonal vitamin D at the carbon 3 position via a scaffold of discreet length. This design facilitates purification, detection, solubility, and efficacy at the PTH receptor (PTHR). The PTH may be conjugated to the non-hormonal vitamin D through a 36 mer poly(ethylene glycol) moiety, known as PTH-PEG36-VitD. This innovative peptide demonstrates a vastly improved serum half-life and bioavailability compared to non-conjugated PTH peptides. Additionally, PTH-PEG36-VitD significantly increases serum calcium, reduces urinary calcium, and lowers serum phosphate levels.
Career Highlights
Caroline is currently associated with Extend Biosciences, Inc., where she continues to advance her research and development efforts. Her work is characterized by a commitment to improving therapeutic options for patients with hormonal deficiencies.
Collaborations
Some of her notable coworkers include Tarik Soliman and Daniel B Hall, who contribute to the collaborative environment at Extend Biosciences, Inc. Their combined expertise enhances the innovative potential of their projects.
Conclusion
Caroline Hill's contributions to the field of biotechnology, particularly through her patent for long-acting parathyroid hormone peptides, showcase her dedication to advancing medical science. Her work has the potential to improve patient outcomes and redefine treatment protocols in endocrinology.