This inventor holds 1 USPTO granted patent. Top assignee: Coulter Corporation. Active years: 1989.
Company Filing History:
Years Active: 1989
Title: Carole Sullivan: Innovator in Monoclonal Antibody Development
Introduction
Carole Sullivan is a notable inventor based in Miami, FL, recognized for her significant contributions to the field of immunology. She has developed a groundbreaking monoclonal antibody that specifically targets HIV antigens, showcasing her expertise and dedication to advancing medical science.
Latest Patents
Carole Sullivan holds a patent for a monoclonal antibody specific to HIV antigens. This invention involves a hybrid cell line capable of producing monoclonal antibodies that bind to HIV core antigen P55, the precursor protein coded for the gag gene, as well as core protein P24 and its partial breakdown products P39 and P33. Importantly, the monoclonal antibody does not bind to the P18 core protein or any HIV envelope antigens. The unique immunization protocol used in developing this cell line involved multiple infusions of selected immunogens and a conventional myeloma cell line for fusion with murine splenocytes. The monoclonal antibody is identified as the KC-57 antibody and is particularly useful for solid-phase immunoassays to detect HIV antigens in serum or plasma samples from human patients. The cell line producing the KC-57 monoclonal antibody has been deposited in the American Type Culture Collection, Rockville, MD, and assigned A.T.C.C. No. HB 9585.
Career Highlights
Carole Sullivan has made significant strides in her career, particularly through her work at Coulter Corporation. Her innovative research and development efforts have contributed to advancements in the detection and treatment of HIV, making a lasting impact on public health.
Collaborations
Throughout her career, Carole has collaborated with esteemed colleagues, including Kenneth H Kortright and David E Hofheinz. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in the field of immunology.
Conclusion
Carole Sullivan's work in developing a monoclonal antibody specific to HIV antigens exemplifies her commitment to innovation in medical research. Her contributions continue to influence the field and improve diagnostic methods for HIV detection.