Cambridge, MA, United States of America

Carlos Lois-Caballe


 

 

Average Co-Inventor Count = 3.9

ph-index = 6

Forward Citations = 93(Granted Patents)


Location History:

  • South Pasadena, CA (US) (2008 - 2016)
  • Cambridge, MA (US) (2010 - 2020)

Company Filing History:


Years Active: 2008-2020

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16 patents (USPTO):Explore Patents

Title: Overview of Inventor Carlos Lois-Caballe

Introduction

Carlos Lois-Caballe is a prominent innovator based in Cambridge, MA, with a notable portfolio that includes 16 patents. His work primarily focuses on the expression of small RNA molecules, contributing significantly to advancements in molecular biology and antiviral technologies.

Latest Patents

Among his latest patents, Carlos developed a method for the expression of small antiviral RNA molecules with reduced cytotoxicity within a cell. This invention provides methods and compositions for expressing small RNA molecules within a cell using a retroviral vector. This innovative technique enables the expression of small interfering RNA (siRNA) to interfere with the lentiviral life cycle. Additionally, he has created methods that allow for the expression of siRNA capable of downregulating CCR5, ensuring minimal cytotoxicity to the host cells. Another significant patent focuses on expressing small RNA molecules using a lentiviral vector, facilitating the generation of transgenic animals by downregulating specific genes in various cell types, including embryonic stem cells.

Career Highlights

Carlos Lois-Caballe has collaborated with prominent research institutions, including the California Institute of Technology and the University of California. Throughout his career, he has demonstrated a commitment to advancing genetic and antiviral research, showcasing his innovative skills through multiple patents.

Collaborations

In his endeavors, Carlos has worked alongside esteemed colleagues such as David Baltimore and Xiao-Feng Qin. These collaborations have further enriched his research, leading to groundbreaking advancements in the field of molecular biology.

Conclusion

Carlos Lois-Caballe's contributions to the field of genetics and antiviral research through his innovations and patents underscore his significance as an inventor. His work continues to influence the scientific community, impacting future research and development in molecular biology.

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