Carl O Pabo

Title: Innovations of Carl O Pabo in Genomic Research

Introduction

Carl O Pabo is a prominent inventor based in Mill Valley, CA (US). He has made significant contributions to the field of genomic research, holding a total of 5 patents. His work focuses on methods and compositions that enhance targeted genomic alterations.

Latest Patents

One of Carl O Pabo's latest patents involves methods and compositions for targeted cleavage and recombination. This patent discloses innovative techniques for the targeted cleavage of genomic sequences, as well as methods for altering and recombining these sequences with exogenous polynucleotides. The compositions he developed include fusion proteins that consist of a cleavage domain and an engineered zinc finger domain, along with polynucleotides that encode these components. The methods for targeted cleavage involve the introduction of these fusion proteins or their encoding polynucleotides into cells. Additionally, the methods for targeted recombination include the introduction of exogenous polynucleotides into cells that contain the disclosed fusion proteins.

Career Highlights

Carl O Pabo is currently associated with Sangamo Biosciences, Inc., where he continues to advance his research in genomic technologies. His work has been instrumental in developing innovative solutions for genetic engineering and therapeutic applications.

Collaborations

Throughout his career, Carl has collaborated with notable colleagues, including Jeffrey C Miller and Fyodor Urnov. These collaborations have further enriched his research and contributed to the advancement of genomic science.

Conclusion

Carl O Pabo's contributions to genomic research through his innovative patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in genetic engineering and therapeutic applications.