Newton, MA, United States of America

Carl O Pabo



Average Co-Inventor Count = 2.4

ph-index = 7

Forward Citations = 1,503(Granted Patents)


Company Filing History:


Years Active: 1998-2011

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15 patents (USPTO):Explore Patents

Title: The Innovations of Carl O Pabo

Introduction

Carl O Pabo is a distinguished inventor based in Newton, MA, known for his significant contributions to the field of biochemistry and molecular biology. With a total of 15 patents to his name, Pabo has made remarkable advancements in the understanding and application of peptide and protein interactions.

Latest Patents

Among his latest patents, one notable invention is related to dimerizing peptides. This invention provides nonnaturally occurring dimerizing peptides and methods for their production. Such peptides are useful for mediating the association of linked functional protein domains. In particular, these peptides facilitate the association of complexes of multiple zinc finger proteins, thereby affording greater specificity and/or affinity in binding to proximately spaced target segments. Another significant patent involves poly zinc finger proteins with improved linkers. This patent discloses polynucleotides encoding chimeric proteins and methods for their production and use. The chimeric proteins comprise a flexible linker between two zinc finger DNA-binding domains, wherein the linker contains eight or more amino acids between the second conserved histidine residue of the carboxy-terminal zinc finger of the first domain and the first conserved cysteine residue of the amino-terminal zinc finger of the second domain.

Career Highlights

Carl O Pabo has had a notable career, primarily associated with the Massachusetts Institute of Technology. His work has significantly impacted the field of protein engineering and molecular biology, leading to advancements that have practical applications in various scientific domains.

Collaborations

Throughout his career, Pabo has collaborated with esteemed colleagues, including Jin-Soo Kim and Joel L Pomerantz. These collaborations have further enriched his research and contributed to the development of innovative solutions in his field.

Conclusion

Carl O Pabo's contributions to science through his patents and collaborations highlight his role as a leading inventor in biochemistry. His work continues to influence the understanding of protein interactions and their applications in technology and medicine.

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