This inventor holds 1 USPTO granted patent. Top assignee: University of California. Active years: 2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2002
Title: Innovations in Oral Delivery Systems by Carl F Grove
Introduction
Carl F Grove is an accomplished inventor based in Portola Valley, California. He has made significant contributions to the field of biopolymer therapeutic agents, particularly in the oral delivery of peptides and proteins. His innovative work has led to the development of a unique system that enhances the effectiveness of these therapeutic agents.
Latest Patents
Carl F Grove holds a patent for "Particles for oral delivery of peptides and proteins." This patent describes microfabricated, asymmetrical, reservoir-containing particles designed for the oral delivery of biopolymer therapeutic agents such as peptides, proteins, and oligonucleotides. The particles are encapsulated in enteric-coated capsules or tablets, allowing them to pass through the stomach and release a suspension of the particles in the intestinal lumen. The particles are engineered with a selected shape and uniform dimensions, preferably in the range of 100 µm to 1 mm. The reservoirs within the particles are filled with therapeutic agents and selected excipients, which are chosen to delay the dissolution and release of the agent for 5 to 60 minutes after the particles are released in the intestinal lumen. Additionally, the face of the particle is grafted with a layer of muco-adhesive ligands, designed to bind the particle to the intestinal mucosa for an extended period after release.
Career Highlights
Carl F Grove is affiliated with the University of California, where he continues to advance research in the field of oral delivery systems. His work has garnered attention for its potential to improve the efficacy of therapeutic agents, making significant strides in medical technology.
Collaborations
Some of his notable coworkers include Mauro Ferrari and Peter J Dehlinger, who have contributed to the research and development of innovative solutions in the field.
Conclusion
Carl F Grove's contributions to the field of oral delivery systems represent a significant advancement in the delivery of biopolymer therapeutic agents. His innovative approach has the potential to enhance treatment efficacy and improve patient outcomes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
