Company Filing History:
Years Active: 2020
Title: Can Pham: Innovator in Cancer Therapeutics
Introduction
Can Pham is a notable inventor based in New York, NY (US), recognized for his contributions to cancer research and therapeutics. He has developed innovative methods that leverage biomarkers to enhance the effectiveness of cancer treatments. His work is particularly focused on the use of rapamycin analogs in cancer therapy.
Latest Patents
Can Pham holds a patent titled "Biomarkers for response to rapamycin analogs." This invention relates to the use of one or more biomarkers to evaluate the likelihood that a rapamycin analog would produce an anti-cancer effect in a subject. The patent is based on experiments that utilized an integrated next-generation sequencing approach to analyze tumor specimens. These experiments aimed to understand intra-tumor and intertumor heterogeneity and the oncogenomic basis of therapeutic benefits in kidney cancer patients. The findings indicated that loss of function mutations in TSC1 and/or TSC2 and/or gain-of-function of mTOR play a significant role in the therapeutic responsiveness to rapamycin analogs. The invention provides assay methods and kits for determining the presence of these mutations, which can aid in selecting appropriate therapeutic regimens for cancer patients.
Career Highlights
Can Pham is affiliated with the Memorial Sloan Kettering Cancer Center, where he conducts his research and develops his inventions. His work has significantly contributed to the understanding of cancer treatment and the development of personalized medicine approaches.
Collaborations
Can Pham has collaborated with esteemed colleagues such as James Hsieh and Michael Berger. These collaborations have further enriched his research and innovation in the field of cancer therapeutics.
Conclusion
Can Pham is a pioneering inventor whose work in cancer therapeutics has the potential to transform treatment approaches for patients. His innovative use of biomarkers to evaluate therapeutic responses exemplifies the intersection of research and practical application in medicine.