This inventor holds 5 USPTO granted patents. Top assignee: Agouron Pharmaceuticals, Inc.. Active years: 2001-2005.
Company Filing History:
Years Active: 2001-2005
Title: Camran V Parast: Innovator in Protein Engineering
Introduction
Camran V Parast is a notable inventor based in San Diego, CA. He has made significant contributions to the field of protein engineering, particularly in the study of vascular endothelial growth factor receptor 2 (VEGFR2/KDR). With a total of 5 patents to his name, Parast's work has implications for therapeutic advancements in various disease conditions.
Latest Patents
One of his latest patents involves modifications of the VEGF receptor-2 protein and methods of use. This patent describes a 2.4 Å crystal structure of a protein construct containing the catalytic kinase domain of VEGFR2/KDR, which is a key enzyme in angiogenesis. The protein construct features a modified catalytic linker and demonstrates comparable in vitro kinase activity to constructs containing the entire KID. Importantly, this construct allows for complete crystallization of the protein, enabling characterization through X-ray crystallography. The invention also discloses the use of X-ray crystallographic data for identifying and constructing potential therapeutic compounds for treating various diseases.
Career Highlights
Camran V Parast is currently associated with Agouron Pharmaceuticals, Inc., where he continues to advance his research in protein engineering. His innovative work has positioned him as a key figure in the development of therapeutic strategies targeting angiogenesis.
Collaborations
Throughout his career, Parast has collaborated with notable colleagues, including Chris Pinko and Anna M Tempcyzk-Russell. These collaborations have further enriched his research and contributed to the success of his projects.
Conclusion
Camran V Parast's contributions to the field of protein engineering, particularly through his patents related to VEGFR2/KDR, highlight his role as an influential inventor. His work not only advances scientific understanding but also paves the way for potential therapeutic applications.