This inventor holds 1 USPTO granted patent. Top assignee: Jiangnan University. Active years: 2020.
Company Filing History:
Years Active: 2020
Title: Innovations of CaiZhe Zhang in Microbial Synthesis
Introduction
CaiZhe Zhang is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of microbial technology, particularly in the synthesis of valuable compounds. His innovative work has led to the development of a unique single-cell factory that efficiently synthesizes α-aminobutyric acid.
Latest Patents
CaiZhe Zhang holds a patent for a "Single-cell factory for efficiently synthesizing α-aminobutyric acid and construction and application thereof." This invention addresses the technical field of microorganisms. The patent describes a method that expresses an L-threonine deaminase gene, an L-amino acid dehydrogenase gene, and a dehydrogenase gene to construct a recombinant single-cell factory. This factory is designed to synthesize α-aminobutyric acid efficiently. The invention optimizes the expression level of the L-threonine deaminase using an RBS sequence, solving the issue of transformation inhibition caused by the accumulation of ketobutyric acid. The overall yield of the recombinant single-cell factory can reach 204 g·L within 20 hours in a 5 L fermentation tank, showcasing its potential for industrial production.
Career Highlights
CaiZhe Zhang is affiliated with Jiangnan University, where he continues to advance his research in microbial synthesis. His work has garnered attention for its practical applications in industrial settings. With a focus on optimizing production processes, Zhang's contributions are paving the way for more efficient biotechnological solutions.
Collaborations
CaiZhe Zhang has collaborated with notable colleagues, including Junping Zhou and Zhiming Rao. Their combined expertise enhances the research and development efforts in the field of microbial technology.
Conclusion
CaiZhe Zhang's innovative work in the synthesis of α-aminobutyric acid through microbial technology exemplifies the potential of modern biotechnological advancements. His contributions are significant for both academic research and industrial applications.