Caili Sun

Title: Caili Sun: Innovator in Gene Engineering

Introduction

Caili Sun is a prominent inventor based in ZiBo, China. He has made significant contributions to the field of gene engineering, particularly in the development of recombinant strains with high lipid yields. His innovative work has the potential to impact various industrial applications.

Latest Patents

Caili Sun holds a patent titled "Construction of accumulating strain and industrial application of constructed strain." This invention relates to a method for constructing non-de novo synthesized recombinant strains with high lipid yield. The method involves overexpressing a diacylglycerol acyltransferase gene (DGAT) in WJ11 through homologous recombination technology. By adding exogenous oil for fermentation, the recombinant strain is constructed, which shows an increased fat yield compared to the control strain Mc2075. Furthermore, when the DGAT is transformed into the uracil defective type of WJ11, the fatty acid composition changes after fermentation, allowing the lipid content to reach 53% of dry cell weight after optimizing fermentation conditions.

Career Highlights

Caili Sun is affiliated with Shandong University of Technology, where he continues to advance his research in gene engineering. His work has garnered attention for its innovative approach to enhancing lipid production through genetic modifications.

Collaborations

Caili has collaborated with notable colleagues, including Meiling Chen and Huaiyuan Zhang. Their combined expertise contributes to the success of their research projects and innovations in the field.

Conclusion

Caili Sun's contributions to gene engineering exemplify the potential of innovative research in biotechnology. His patented methods for constructing recombinant strains with high lipid yields are paving the way for advancements in industrial applications.