Caifen Zhang

Title: Innovations of Caifen Zhang in PCR Sequencing Methods

Introduction

Caifen Zhang is a notable inventor based in Guangdong, China. He has made significant contributions to the field of genetic analysis through his innovative approaches to PCR sequencing methods. His work focuses on enhancing the efficiency and applicability of DNA barcoding techniques in HLA genotyping.

Latest Patents

Caifen Zhang holds a patent for the "Application of a PCR sequencing method, based on DNA barcoding technique and DNA incomplete shearing strategy, in HLA genotyping." This invention provides a PCR sequencing method that combines primer indexes, a DNA incomplete shearing strategy, and second-generation sequencing techniques, specifically the Paired-End sequencing technique. This combination allows for longer PCR products to be sequenced than the maximum sequencing length of the sequencer. It effectively utilizes the high throughput and low-cost characteristics of second-generation sequencing, thereby broadening its applicable scope. Additionally, the invention includes primer indexes for the PCR sequencing method and its application in genotyping, particularly in HLA analysis, along with the specific PCR primers for HLA-A, B, HLA-C, and HLA-DQB1 genes.

Career Highlights

Caifen Zhang is currently associated with BGI Genomics Co., Limited, where he continues to advance his research and innovations in genomics. His work has positioned him as a key figure in the field, contributing to the development of more efficient genetic testing methods.

Collaborations

Caifen Zhang has collaborated with notable colleagues, including Jian Li and Shiping Chen, who have contributed to his research endeavors.

Conclusion

Caifen Zhang's innovative work in PCR sequencing methods exemplifies the advancements being made in genetic analysis. His contributions are paving the way for more efficient and cost-effective solutions in HLA genotyping.