Company Filing History:
Years Active: 1992-1999
Title: C Joseph Welter: Innovator in Veterinary Vaccines
Introduction
C Joseph Welter is a notable inventor based in Des Moines, IA (US). He has made significant contributions to the field of veterinary medicine, particularly in the development of vaccines for swine. With a total of 5 patents to his name, Welter's work has had a profound impact on animal health.
Latest Patents
One of Welter's latest patents is titled "Inactivated Mycoplasma hyopneumoniae and uses therefor." This invention relates to a method for creating an inactivated vaccine for Mycoplasma hyopneumoniae by using Thimerosal to inactivate the bacteria. The resulting bacterin is combined with an adjuvant of aluminum hydroxide and DEAE dextran, which is then injected into pigs. This innovative approach not only provides protective immunity against mycoplasmal pneumonia but also allows for the mixture to be combined with other bacteria such as Bordetella and Pasteurella for enhanced adjuvant effects.
Another significant patent is for the "Isospora suis sporozoite antigen." In this invention, Isospora suis is propagated using a swine testicular cell line, facilitating the production of sporozoites and merozoites for use in vaccines. Welter's research led to the creation of neutralizing antibodies against Isospora suis sporozoites, which inhibit their infectivity. This work has identified a sporozoite attachment protein, and the corresponding cDNA was sequenced, revealing areas with repeated amino acid sequences that may also be utilized in vaccine development.
Career Highlights
Welter is currently associated with Ambico, Inc., where he continues to innovate in the field of veterinary vaccines. His work has been instrumental in advancing the health and well-being of swine, contributing to the agricultural industry.
Collaborations
Welter has collaborated with notable coworkers, including Mark W Welter and Gerald R Fitzgerald, who have supported his research endeavors.
Conclusion
C Joseph Welter's contributions to veterinary medicine through his innovative patents have significantly advanced the field of swine health. His work exemplifies the importance of research and development in creating effective vaccines for animal diseases.