Cécile Buhot

Title: Cécile Buhot: Innovator in HLA-DP4 Ligand Selection

Introduction

Cécile Buhot is a notable inventor based in Vitry-sur-Seine, France. He has made significant contributions to the field of biochemistry, particularly in the area of ligand selection for HLA-DP4. His innovative methods have implications for various applications in medical research and therapeutic development.

Latest Patents

Cécile Buhot holds a patent for a method of selecting HLA-DP4 ligands. This method involves incubating HLA-DP4 with a test molecule and a labeled peptide, forming respective complexes. The process includes separating these complexes, detecting the HLA-DP4/labeled peptide complexes, and selecting the test molecule that demonstrates a binding activity of IC₅₀ < 1000 nM. This innovative approach is crucial for understanding molecular interactions and developing targeted therapies.

Career Highlights

Throughout his career, Cécile Buhot has worked with prominent organizations, including the Commissariat à l'Énergie Atomique and Sedac Therapeutics. His experience in these institutions has allowed him to refine his skills and contribute to groundbreaking research in the field of immunology.

Collaborations

Cécile Buhot has collaborated with esteemed colleagues such as Bernard Maillere and Florence Castelli. These partnerships have fostered a collaborative environment that enhances the quality and impact of their research.

Conclusion

Cécile Buhot's contributions to the field of ligand selection for HLA-DP4 are noteworthy. His innovative methods and collaborations have the potential to advance medical research and therapeutic applications significantly.