Company Filing History:
Years Active: 2011
Title: Innovations by Byeong Chang
Introduction
Byeong Chang is an accomplished inventor based in Hayward, CA. He has made significant contributions to the field of pharmaceuticals, particularly in the development of stable peptide formulations. His innovative work has led to the creation of a patented formulation that enhances the stability and usability of therapeutic peptides.
Latest Patents
Byeong Chang holds a patent for a high temperature stable peptide formulation. This stabilized pharmaceutical composition is designed as a lyophilized product that can be reconstituted to generate an aqueous drug product. The patent describes a therapeutically active peptide with the sequence TDLQERGDNDISPFSGDGQPFKD, which is stabilized using a combination of a buffer, carbohydrate stabilizer, nonionic bulking agent, and surfactant. This formulation has demonstrated exceptional stability when stored at elevated temperatures, maintaining its integrity for at least six months at 40°C and three months at 50°C. Additionally, the formulation can be terminally sterilized using gamma irradiation without compromising the stability of the active ingredient.
Career Highlights
Byeong Chang is currently associated with Acologix, Inc., where he continues to innovate in the pharmaceutical sector. His work focuses on enhancing the stability and effectiveness of peptide-based therapies, which are crucial for various medical applications.
Collaborations
He collaborates with notable colleagues, including Dennis Chen and Russell Wayne Blacher, who contribute to the research and development efforts at Acologix, Inc.
Conclusion
Byeong Chang's contributions to the field of pharmaceuticals through his innovative peptide formulation highlight the importance of stability in drug development. His work not only advances therapeutic options but also sets a standard for future innovations in the industry.