Bruno Bruni Ercole is a notable inventor based in Rome, Italy. He has made significant contributions to the field of biotechnology, particularly in the development of vaccine carriers. With a total of 2 patents, his work focuses on innovative methods for delivering immunogens to enhance immune responses.

Latest Patents

One of his latest patents involves the creation of chimpanzee adenovirus vaccine carriers. This invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses. It also outlines methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention includes compositions and methods suitable for delivering and expressing transgenes that encode immunogens, which are essential for eliciting a boosted immune response. Furthermore, it details methods for generating clinical-grade vector stocks suitable for human use. A particular embodiment of this invention contemplates the use of vectors that comprise transgenes encoding tumor-associated antigens in vaccines and pharmaceutical compositions aimed at preventing and treating cancer.

Career Highlights

Bruno Bruni Ercole has worked with esteemed organizations such as Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A. and MSD Italia S.r.l. His experience in these institutions has contributed to his expertise in molecular biology and vaccine development.

Collaborations

Throughout his career, he has collaborated with notable colleagues, including Stefano Colloca and Alfredo Nicosia. These partnerships have likely enhanced his research and innovation capabilities.

Conclusion

Bruno Bruni Ercole's contributions to vaccine technology and molecular biology are noteworthy. His innovative patents and collaborations reflect his commitment to advancing medical science. His work continues to have a significant impact on the field of immunology and cancer treatment.

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