Company Filing History:
Years Active: 1989
Title: Bruce Mico: Innovator in Pharmaceutical Chemistry
Introduction
Bruce Mico is a notable inventor based in Bridgewater, NJ (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of prodrug carbamate derivatives.
Latest Patents
Mico holds a patent for "Carbamates of - Prodrug carbamate derivatives of fenoldopam." This innovative patent provides fenoldopam plasma levels of similar magnitude and over a much longer period of time than the parent compound. Notably, it addresses the absence of a high initial peak effect associated with the parent compound. A lead compound of this series is 6-chloro-7,8-diethylcarbamoyl-1-(4'-ethylcarbamoylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine. The R-enantiomers are identified as the most biologically active and preferred compounds.
Career Highlights
Bruce Mico is associated with SmithKline Beckman Corporation, where he has been instrumental in advancing pharmaceutical research. His work has contributed to the understanding and application of prodrug formulations in clinical settings.
Collaborations
Mico has collaborated with esteemed colleagues such as Dimitri E Gaitanopoulos and Joseph Weinstock, enhancing the research and development efforts within his field.
Conclusion
Bruce Mico's innovative work in pharmaceutical chemistry, particularly with prodrug carbamate derivatives, showcases his commitment to advancing medical science. His contributions continue to impact the field positively.