This inventor holds 1 USPTO granted patent and 3 published patent applications and 2 EPO patents. Top assignees: Indiana University, The Jackson Laboratory. Active years: 2024.
Company Filing History:
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Years Active: 2024
Title: Bruce Lamb: Innovator in Alzheimer's Research
Introduction
Bruce Lamb is a prominent inventor based in Carmel, IN (US). He has made significant contributions to the field of Alzheimer's research through his innovative work in genetic modifications. His research focuses on understanding the mechanisms of Alzheimer's disease, particularly through the development of genetically modified mice.
Latest Patents
Bruce Lamb holds a patent for a genetically modified mouse expressing human APOE4 and mouse Trem2 p.R47H. This invention provides a model characterized by symptoms relevant to non-familial late-onset Alzheimer's disease. The genome of the mouse includes a DNA sequence encoding a human APOE4 protein operably linked to a promoter, as well as a DNA sequence encoding a mouse Trem2 protein with a mutation p.R47H. This model is essential for screening compounds for potential treatments for Alzheimer's disease.
Career Highlights
Throughout his career, Bruce Lamb has worked with notable institutions, including Indiana University and The Jackson Laboratory. His research has been pivotal in advancing the understanding of Alzheimer's disease and developing potential therapeutic strategies.
Collaborations
Bruce has collaborated with Gregory Carter, contributing to the advancement of research in the field of Alzheimer's disease.
Conclusion
Bruce Lamb's innovative work in genetic modifications has significantly impacted Alzheimer's research. His contributions continue to pave the way for new treatments and a deeper understanding of this complex disease.