Bruce J Baum

Title: Bruce J Baum: Innovator in Genetic Engineering

Introduction

Bruce J Baum is a prominent inventor based in Bethesda, MD (US). He has made significant contributions to the field of genetic engineering, holding a total of 6 patents. His work focuses on the development of innovative nucleic acids and viral vectors that have potential applications in medicine.

Latest Patents

One of his latest patents is titled "Nucleic acids encoding growth hormone with a modified RSP sorting signal." This invention provides a nucleic acid molecule encoding a growth hormone (GH) that can be constitutively secreted by the nonregulated secretory pathway (NRSP) in a mammalian cell. The modification of the RSP sorting signal allows for enhanced secretion of GH, which could have important implications for therapeutic applications.

Another notable patent is the "Hybrid adeno-retroviral vector for the transfection of cells." This invention describes an adenovirus that includes adenoviral capsid proteins and a replication-defective adenoviral vector. The vector is designed to facilitate the introduction of transgenes into host cells, which can be crucial for gene therapy and other medical interventions.

Career Highlights

Bruce J Baum is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this esteemed institution has allowed him to collaborate with leading scientists and contribute to groundbreaking research in the field of genetic engineering.

Collaborations

Some of his notable coworkers include Changyu Zheng and Brian Christopher O'Connell. Their collaborative efforts have further advanced the research and development of innovative genetic technologies.

Conclusion

Bruce J Baum's contributions to genetic engineering through his patents and research at the National Institutes of Health highlight his role as a key innovator in the field. His work continues to pave the way for advancements in medical science and therapeutic applications.