The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2011
Filed:
Sep. 06, 2007
Yoke Peng Loh, Bethesda, MD (US);
Niamh Cawley, Bethesda, MD (US);
Bruce J. Baum, Bethesda, MD (US);
Christopher R. Snell, Norfolk, GB;
Yoke Peng Loh, Bethesda, MD (US);
Niamh Cawley, Bethesda, MD (US);
Bruce J. Baum, Bethesda, MD (US);
Christopher R. Snell, Norfolk, GB;
Abstract
The invention provides a nucleic acid molecule encoding a growth hormone (GH) in which the RSP sorting signal has been mutated, such that the GH can be constitutively secreted by the nonregulated secretory pathway (NRSP) in a mammalian cell. The invention also provides a nucleic acid molecule encoding a GH in which the three-dimensional conformation of the RSP sorting signal has been altered such that the GH can be constitutively secreted by the NRSP in a mammalian cell.