Company Filing History:
2 out of 30 
1 out of 31 
1 out of 7 Years Active: 2013-2018
Title: Brian Stephen Sproat: Innovator in Oligonucleotide Synthesis
Introduction
Brian Stephen Sproat is a notable inventor based in Booischot, Belgium. He has made significant contributions to the field of oligonucleotide synthesis, holding a total of four patents. His work focuses on enhancing the methods and applications of oligonucleotides, which are essential in various biotechnological and pharmaceutical applications.
Latest Patents
One of his latest patents is titled "Oligonucleotides containing high concentrations of guanine monomers." This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. The invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. Furthermore, the invention includes oligonucleotides obtainable by the methods described.
Another significant patent is "Purification of triphosphorylated oligonucleotides using capture tags." This invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows for the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity, making them suitable for pharmaceutical applications.
Career Highlights
Brian has worked with esteemed institutions, including Rheinische Friedrich Wilhelms-Universität Bonn and Cytos Biotechnology AG. His experience in these organizations has contributed to his expertise in the field of oligonucleotide research and development.
Collaborations
Throughout his career, Brian has collaborated with notable colleagues such as Janos Ludwig and Marion Goldeck. These collaborations have further enriched his work and expanded the impact of his inventions.
Conclusion
Brian Stephen Sproat is a distinguished inventor whose work in oligonucleotide synthesis has led to significant advancements in the field. His patents reflect his commitment to innovation and the development of methods that enhance the efficacy of oligonucleotides in various applications.
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