Brian R White

Title: Innovations and Contributions of Inventor Brian R. White

Introduction

Brian R. White is a notable inventor based in Clayton, MO (US), recognized for his significant contributions to the field of genomics and brain function mapping. With a total of six patents to his name, he has made strides in developing innovative technologies that enhance the understanding and treatment of complex medical conditions.

Latest Patents

One of Brian R. White's latest patents is titled "Automated exposition of known and novel multiple myeloma genomic variants using a single sequencing platform." This invention discloses a sequencing capture array designed to identify mutations in Multiple Myeloma. The technology includes targeted next-generation sequencing methods for detecting single nucleotide variants (SNV), copy number variations (CNV), and translocation mutations in Multiple Myeloma tumor cells. The capture array focuses on fewer than 500 genes implicated in Multiple Myeloma, enabling the analysis of tumor mutations and the creation of personalized treatment plans for patients. The analytical methods presented allow for elucidating tumor mutations with coverage at a sequencing depth of no more than 500×, or as low as 100×, achieving optimal efficiency at around 300×.

Another significant patent is "Task-less optical mapping of dynamic brain function using resting state functional connectivity." This method utilizes an optical system for mapping brain function by determining a time series of light intensity measurements from spatially distributed source and detector pairs. The process involves receiving light measurements over time and producing maps that represent the strength of various temporal correlations based on these measurements.

Career Highlights

Throughout his career, Brian R. White has worked with prominent organizations, including Amazon Technologies, Inc. and Washington University. His experience in these institutions has contributed to his innovative research and development efforts in the fields of genomics and neuroscience.

Collaborations

Brian has collaborated with notable colleagues such as Lee A. Atchison and Peter D. Cohen, further enhancing the impact of his work through shared expertise and insights.

Conclusion

Brian R. White's contributions to the fields of genomics and brain function mapping exemplify the spirit of innovation. His patents reflect a commitment to advancing medical science and improving patient care through technology.