This inventor holds 2 USPTO granted patents. Top assignee: Washington University. Active years: 2015-2019.
Location History:
- Manchester, MO (US) (2015)
- St. Louis, MO (US) (2019)
Company Filing History:
Years Active: 2015-2019
Title: Innovations in Cardiac Imaging by Brian P Cupps
Introduction
Brian P Cupps is an accomplished inventor based in St. Louis, MO. He has made significant contributions to the field of cardiac imaging, particularly through his innovative methods for measuring cardiac strain. With a total of 2 patents, Cupps has developed advanced techniques that enhance the understanding of myocardial function.
Latest Patents
Cupps' latest patents include groundbreaking systems and methods for measuring cardiac strain. One of his notable inventions is a method for rapid computation of three-dimensional displacement and Lagrange strain in high-resolution fields of phase data obtained with Displacement Encoding with Stimulated Echoes (DENSE) in magnetic resonance images of the myocardium. This method incorporates semi-automated segmentation of a heart region, phase unwrapping in three dimensions, and a custom radial point interpolation method (RPIM). The RPIM utilizes meshfree numerical analysis with radial basis functions and polynomial functions to calculate the Lagrange strain of DENSE displacement data from the myocardium.
Another significant patent is a method for quantitatively mapping myocardial contractile function using magnetic resonance-based multiparametric strain analysis. This technique determines strain at various locations in a subject's heart by acquiring a series of MR images with a tagging pulse sequence (SPAMM). The method calculates circumferential strain, longitudinal strain, and the minimum principal strain angle at different heart locations. These raw strain values are normalized against a stored reference heart model, resulting in a composite multiparametric strain index that reflects myocardial contractile function.
Career Highlights
Cupps is affiliated with Washington University, where he continues to advance research in cardiac imaging. His work has been instrumental in developing non-invasive techniques that provide valuable insights into heart function.
Collaborations
Cupps collaborates with esteemed colleagues, including Michael K Pasque and Julia Kar, to further enhance the impact of his research in the medical field.
Conclusion
Brian P Cupps is a notable inventor whose innovations in cardiac imaging are paving the way for improved diagnostic techniques. His contributions are vital for advancing the understanding of myocardial function and enhancing patient care.