Brian L Hood

Title: Brian L Hood: Innovator in Antibody Research

Introduction

Brian L Hood is a notable inventor based in Reston, VA (US). He has made significant contributions to the field of biomedical research, particularly in the development of antibodies for cancer treatment. With a total of 4 patents to his name, Hood's work is paving the way for advancements in targeted therapies.

Latest Patents

Hood's latest patents focus on isolated monoclonal antibodies that specifically bind to endoplasmin. These antibodies are designed to be fully human in some embodiments. The patents also disclose recombinant nucleic acids encoding these antibodies, expression vectors that include these nucleic acids, and host cells transformed with these expression vectors. The disclosed antibodies have potential applications in detecting and treating tumors that express endoplasmin, including melanoma, breast cancer, head and neck squamous cell carcinoma, renal cancer, lung cancer, glioma, bladder cancer, ovarian cancer, and pancreatic cancer. One specific example highlighted is the use of these antibodies in treating melanoma.

Career Highlights

Brian L Hood is affiliated with the University of Pittsburgh, where he continues to advance his research in antibody development. His work has garnered attention for its potential impact on cancer therapies, making him a key figure in the field.

Collaborations

Hood collaborates with esteemed colleagues such as Soldano Ferrone and Xinhui Wang, contributing to a rich environment of innovation and research.

Conclusion

Brian L Hood's contributions to antibody research exemplify the intersection of innovation and medical science. His patents and ongoing work hold promise for improving cancer treatment options in the future.