Company Filing History:
Years Active: 2018-2023
Title: Brian James Leppert: Innovator in Genetic Therapies
Introduction
Brian James Leppert is a notable inventor based in Kenmore, WA (US). He has made significant contributions to the field of genetic therapies, holding a total of 4 patents. His work focuses on innovative methods for treating genetic disorders, particularly those involving expanded nucleotide repeats.
Latest Patents
One of Leppert's latest patents is titled "Oligonucleotides for treating expanded repeat diseases." This invention provides a method for selectively reducing the expression of a mutant mRNA and/or protein that has an expanded nucleotide repeat compared to a wild-type mRNA. The method involves contacting a cell with an antisense oligonucleotide that is sufficiently long and complementary to the expanded nucleotide repeat. This invention is particularly relevant for reducing the expression of the mutant Huntington protein associated with Huntington's disease.
Another significant patent is "Induced exon inclusion in spinal muscle atrophy." This invention relates to the use of an antisense compound to induce exon inclusion as a treatment for Spinal Muscle Atrophy (SMA). Specifically, it focuses on inducing the inclusion of exon 7 to restore levels of Survival Motor Neuron (SMN) protein encoded by the SMN gene.
Career Highlights
Brian James Leppert is currently associated with Sarepta Therapeutics, Inc., a company known for its pioneering work in genetic medicine. His role at the company allows him to contribute to groundbreaking research and development in the field of genetic therapies.
Collaborations
Leppert has collaborated with notable colleagues such as Peter S. Linsley and Gunnar J. Hanson. These collaborations have further enhanced his research and innovation in the field.
Conclusion
Brian James Leppert is a distinguished inventor whose work in genetic therapies has the potential to transform treatment options for various genetic disorders. His innovative patents and collaborations reflect his commitment to advancing medical science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.