Brian Horsburgh is an accomplished inventor based in New Canaan, CT (US). He has made significant contributions to the field of immunotherapy, holding two patents that focus on nanoparticulate compositions designed to enhance immune responses.

Latest Patents

Horsburgh's latest patents include "Nanoparticulate compositions comprising interferon gamma and losartan for immunotherapy" and "Modular particles for immunotherapy." Both patents describe nanoparticulate compositions that typically include one or more active agents, including immunomodulatory compounds. These compositions are loaded into, attached to the surface of, or enclosed within delivery vehicles such as nanolipogels or biodegradable polymeric nanoparticles like PLGA. The active agents are designed to either increase an immune stimulatory response or decrease an immune suppressive response. In some cases, the particles may contain both types of immunomodulators. Additionally, the particles can be decorated with targeting moieties to improve delivery to specific target cells. Methods for using these compositions to enhance immune responses and treat diseases, including cancer, are also disclosed.

Career Highlights

Brian Horsburgh is affiliated with Yale University, where he continues to advance research in immunotherapy. His work has garnered attention for its innovative approach to enhancing immune responses through nanoparticulate technology.

Collaborations

Horsburgh collaborates with Tarek M Fahmy, a fellow researcher at Yale University. Their partnership focuses on developing advanced therapeutic strategies in the field of immunotherapy.

Conclusion

Brian Horsburgh's innovative work in nanoparticulate compositions represents a significant advancement in immunotherapy. His contributions have the potential to improve treatment outcomes for various diseases, including cancer.

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