Company Filing History:
Years Active: 1990-2001
Title: Innovations of Brian H Barber
Introduction
Brian H Barber is a notable inventor based in Mississauga, Canada. He has made significant contributions to the field of immunology through his innovative patents. With a total of 6 patents, Barber's work focuses on enhancing immune responses using advanced antibody technologies.
Latest Patents
One of Barber's latest patents is a method for the delivery of antigens to selected cells of the immune system using chimeric antibodies. This patent describes antibody molecules that are specific for surface structures of antigen-presenting cells. These molecules have been modified to include an antigen moiety at a specific site, resulting in novel conjugate antibody molecules. The production of these conjugate molecules involves genetic modification of genes encoding the light and heavy chains of the surface structure-specific antibody, followed by expression in mammalian cells. The conjugate antibody retains specificity for antigen-presenting cells while containing the antigen moiety. This innovative approach allows for the delivery of antigens to antigen-presenting cells, thereby producing an enhanced immune response in hosts that are immunized with these conjugate antibodies. The conjugate antibody molecules and the nucleic acid molecules encoding them are valuable for use as antigens and immunogens in both diagnostic and prophylactic applications.
Career Highlights
Throughout his career, Barber has worked with prominent companies in the biotechnology sector, including Connaught Laboratories Limited and Aventis Pasteur Limited. His experience in these organizations has contributed to his expertise in developing innovative solutions in immunology.
Collaborations
Barber has collaborated with notable professionals in his field, including George Carayannotis and Naveen N Anand. These collaborations have further enriched his research and development efforts.
Conclusion
Brian H Barber's contributions to immunology through his innovative patents demonstrate his commitment to advancing medical science. His work continues to have a significant impact on the development of new therapeutic strategies.