Location History:
- Pittsburgh, PA (US) (1993)
- Madison, WI (US) (1995)
Company Filing History:
1 out of 2,313 
1 out of 9 
1 out of 1,528 Years Active: 1993-1995
Title: Innovations of Brian G Fox in Environmental Biotechnology
Introduction
Brian G Fox is an accomplished inventor based in Pittsburgh, PA (US). He has made significant contributions to the field of environmental biotechnology, particularly in the degradation of halogenated hydrocarbons. With a total of 2 patents, his work focuses on innovative methods to address environmental challenges.
Latest Patents
One of his latest patents is titled "Rapid degradation of halogenated hydrocarbons by soluble methane." This method discloses a process for degrading halogenated hydrocarbon compounds, such as trichloroethylene (TCE), using a soluble methane monooxygenase or a bacterium that produces this enzyme. The bacterium Methylosinus trichosporium OB3b is highlighted for its capability to degrade TCE at impressive rates, ranging from about 500 to 10,000 micromoles per hour per gram of cells. This method is particularly useful for degrading TCE at initial concentrations of up to 10,000 micromoles/l.
Another significant patent is the "Method for oxidizing hydrocarbons with a hydroxylase from a methane." This patent describes a purified hydroxylase component of the soluble methane monooxygenase enzyme found in Methylosinus trichosporium OB3b. The hydroxylase is capable of oxidizing hydrocarbons under aerobic conditions, utilizing suitable reducing agents. The purification process of the hydroxylase is enhanced by including ferrous iron compounds and cysteine in the extraction buffers.
Career Highlights
Brian G Fox has worked with notable institutions, including the University of Minnesota and Biotrol, Inc. His career reflects a commitment to advancing environmental biotechnology through innovative research and development.
Collaborations
Throughout his career, Brian has collaborated with esteemed colleagues such as John D Lipscomb and Richard S Hanson. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Brian G Fox's innovative work in environmental biotechnology showcases his dedication to finding solutions for pressing environmental issues. His patents reflect a significant contribution to the field, particularly in the degradation of harmful compounds.