Company Filing History:
Years Active: 2021-2024
Title: Brian Betts: Innovator in Graft Versus Host Disease Research
Introduction
Brian Betts is a notable inventor based in Tampa, FL (US), recognized for his contributions to the field of medical research, particularly in the area of graft versus host disease (GVHD). He holds 3 patents that focus on innovative compounds and methods aimed at preventing and treating this serious condition.
Latest Patents
One of Betts' latest patents involves the development of Aurora kinase and Janus kinase inhibitors for the prevention of graft versus host disease. This patent discloses compounds and methods that can reduce the risk of developing, preventing, or treating GVHD in subjects. The compounds are designed to concurrently block Aurora kinase A and JAK2 signal transduction, which synergistically suppresses alloreactive human T-cells in vitro. This innovation prevents xenogeneic graft-versus-host disease without impairing anti-tumor responses and promotes the development and suppressive potency of CD39+ inducible T-cells. Additionally, he has developed methods for identifying patients at risk for developing GVHD and for monitoring the efficacy of therapeutic treatments in subjects receiving hematopoietic stem cell transplantation.
Career Highlights
Brian Betts is affiliated with the H. Lee Moffitt Cancer Center and Research Institute, Inc., where he conducts his research. His work is pivotal in advancing the understanding and treatment of GVHD, contributing significantly to the field of oncology.
Collaborations
Throughout his career, Betts has collaborated with esteemed colleagues, including Said M Sebti and Harshani Lawrence. These partnerships enhance the research efforts and broaden the impact of his work in the medical community.
Conclusion
Brian Betts is a distinguished inventor whose work in graft versus host disease research is making a significant impact in the medical field. His innovative patents and collaborations are paving the way for advancements in treatment and prevention strategies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.