Brian B Masek

Title: Brian B Masek: Innovator in Pharmaceutical Chemistry

Introduction

Brian B Masek is a notable inventor based in West Grove, PA (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds that target hypertension and congestive heart failure. With a total of 2 patents, Masek's work has the potential to impact medical treatments significantly.

Latest Patents

Masek's latest patents include innovative compounds known as 1,6-naphthyridinone derivatives that possess angiotensin II antagonist activity. These compounds are described by a specific formula, where R.sup.1, R.sup.2, R.sup.3, R.sup.4, Ra, Rb, A, X, and Z have various defined meanings. The invention emphasizes the pharmaceutical usefulness of these compounds and their non-toxic salts, as well as the pharmaceutical compositions that contain them. The novel compounds are particularly valuable in treating conditions such as hypertension and congestive heart failure. Additionally, the patents detail processes for manufacturing these compounds and their applications in medical treatment.

Career Highlights

Brian B Masek is associated with Imperial Chemical Industries Limited, where he has been able to apply his expertise in pharmaceutical development. His work has contributed to advancements in the treatment of cardiovascular conditions, showcasing his commitment to improving patient outcomes through innovative chemistry.

Collaborations

Masek has collaborated with notable colleagues, including Arnold H Ratcliffe and Robert J Pearce. These partnerships have likely enhanced the scope and impact of his research and inventions.

Conclusion

Brian B Masek stands out as an influential inventor in the pharmaceutical industry, with a focus on developing compounds that address critical health issues. His contributions through patents and collaborations reflect his dedication to advancing medical science.