Company Filing History:
Years Active: 2021-2024
Title: Bret Holguin: Innovator in Alpha-Synuclein Research
Introduction
Bret Holguin is a prominent inventor based in San Diego, CA. He has made significant contributions to the field of biomedical research, particularly in the study of alpha-synuclein, a protein associated with neurodegenerative diseases. With a total of 4 patents to his name, Holguin's work is paving the way for advancements in diagnostics and therapeutic methods.
Latest Patents
Holguin's latest patents include innovative methods and compositions related to alpha-synuclein. One of his notable patents is for an expression vector designed for the production of human alpha-synuclein (αS) protein or its conservative variants. This vector is optimized to reduce the tendency of the protein to self-aggregate, which is crucial for accurate research and potential therapeutic applications. Another significant patent involves a method for detecting soluble, misfolded α-synuclein protein in biological samples. This method utilizes a pre-incubation mixture and specific beads to determine the presence of misfolded aggregates, which can be indicative of various neurodegenerative conditions.
Career Highlights
Bret Holguin has established himself as a key figure in his field through his work at Amprion, Inc. His research focuses on the implications of alpha-synuclein in diseases such as Parkinson's. His innovative approaches have garnered attention and respect within the scientific community.
Collaborations
Holguin collaborates with talented individuals such as Luis Concha and Carly Farris. These partnerships enhance the research efforts at Amprion, Inc. and contribute to the development of groundbreaking solutions in the realm of neurodegenerative disease research.
Conclusion
Bret Holguin's contributions to the field of alpha-synuclein research are invaluable. His patents and collaborative efforts are instrumental in advancing our understanding of neurodegenerative diseases and developing potential diagnostic and therapeutic strategies.