Location History:
- Burlingame, CA (US) (1999 - 2003)
- San Bruno, CA (US) (2003)
Company Filing History:
Years Active: 1999-2003
Title: The Innovative Contributions of Bret Benton
Introduction
Bret Benton is a notable inventor based in Burlingame, California, recognized for his significant contributions to the field of antibacterial research. With a total of seven patents to his name, Benton has focused on developing methods to combat bacterial infections, particularly those caused by Staphylococcus aureus.
Latest Patents
Benton's latest patents include innovative methods of screening for compounds that are active on Staphylococcus aureus target genes. These disclosures describe isolated or purified deoxyribonucleotide (DNA) sequences that are essential for the development of antibacterial agents. The patents detail the coding sequences of bacterial pathogenesis genes, which are expressed in vivo. Additionally, they describe isolated or purified DNA sequences that serve as probes to identify the presence of corresponding genes or bacteria containing those genes. The patents also cover hypersensitive mutant cells that contain a mutant gene corresponding to the identified sequences, along with methods for screening antibacterial agents using these cells. Furthermore, they outline methods for treating bacterial infections by administering antibacterial agents that target the identified genes, as well as pharmaceutical compositions effective in such treatments.
Career Highlights
Bret Benton has had a distinguished career, working with companies such as Microcide Pharmaceuticals, Inc. and Essential Therapeutics, Inc. His work has significantly advanced the understanding and treatment of bacterial infections, showcasing his commitment to innovation in the field of medicine.
Collaborations
Benton has collaborated with notable colleagues, including Molly B. Schmid and Dongxu Sun, contributing to a rich exchange of ideas and advancements in antibacterial research.
Conclusion
Bret Benton’s innovative work in developing antibacterial agents and methods for screening compounds has made a substantial impact in the fight against bacterial infections. His contributions continue to influence the field and pave the way for future advancements in medical research.