Location History:
- North Ryde, AU (2002 - 2006)
- Tarrytown, NY (US) (2006)
- Lane Cove, AU (2006)
Company Filing History:
Years Active: 2002-2006
Title: Brendon Conlan: Innovator in Biochemical Separation Technologies
Introduction
Brendon Conlan is a notable inventor based in Tarrytown, NY (US). He has made significant contributions to the field of biochemical separation technologies, holding a total of 5 patents. His work focuses on innovative methods for isolating and purifying biomolecules, which are crucial in various medical and therapeutic applications.
Latest Patents
One of Brendon Conlan's latest patents involves the separation of Factor VIII. The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system. This system contains a separation membrane that creates a first and second interstitial volume between at least two restriction membranes. One or more stabilizing agents are added to the sample and/or an interstitial volume. A solvent in the first interstitial volume maintains FVIII in a desired charge state. By applying a potential between the first and second interstitial volumes, FVIII is separated on one side of the separation membrane from unwanted molecules on the other side. These methods may also serve as a substitute for one or more steps in a conventional purification scheme for the separation of native or recombinant FVIII.
Another significant patent addresses the removal of biological contaminants. This method involves placing a biomolecule and contaminant mixture in a first solvent stream, which is separated from a second solvent stream by an electrophoretic membrane. A buffer with a required pH is selected for the first solvent stream. An electric potential is applied between the two solvent streams, causing the biomolecule to move through the membrane into the second solvent stream while retaining the biological contaminant in the first stream. This process can be adjusted to ensure the desired purity of the biomolecule is achieved.
Career Highlights
Brendon Conlan has worked with several companies throughout his career, including Gradipore Limited and Life Therapeutics Limited. His experience in these organizations has contributed to his expertise in biochemical technologies and patent development.
Collaborations
Brendon has collaborated with notable professionals in his field, including Chenicheri Hariharan Nair and Elizabeth Jean Seabrook. These collaborations have further enhanced his innovative approaches to biochemical separation.
Conclusion
Brendon Conlan is a distinguished inventor whose work in biochemical separation technologies has led to significant advancements in the field. His innovative patents and collaborations reflect his commitment to improving biomolecule purification
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