Company Filing History:
Years Active: 2010-2016
Title: Brendan Toohey: Innovator in Biosensor Technology
Introduction
Brendan Toohey is an accomplished inventor based in Clifton Hill, Australia. He has made significant contributions to the field of biosensor technology, holding three patents that showcase his innovative approach to detecting target analytes.
Latest Patents
One of Brendan's latest patents is a biosensor using whispering gallery modes in microspheres. This biosensor is designed to detect the presence of a target analyte through microspheroidal particles that have binding partners immobilized on their surfaces. When the analyte binds to its partner, the whispering gallery mode profiles of the microspheroidal particles change, resulting in a red- or blue-shift in the profile peaks. The immobilized binding partners may include various substances such as nucleotides, peptides, proteins, enzymes, and antibodies, which can also incorporate fluorophores for enhanced detection capabilities.
Another notable patent is a nucleic acid anchoring system comprising covalent linkage of an oligonucleotide to a solid support. This system includes a solid support and a chemical linking moiety that facilitates ether formation with a nucleic acid molecule. The invention is particularly useful for constructing nucleic acid arrays, purifying nucleic acid molecules, and anchoring them for various experimental applications. The system is adaptable for use with microspheres and optical fiber arrays, allowing for versatile applications in molecular biology.
Career Highlights
Brendan has worked with several companies throughout his career, including Genera Biosystems Limited and Mulvaney, Paul. His experience in these organizations has contributed to his expertise in biosensor technology and molecular biology.
Collaborations
Brendan has collaborated with notable individuals in his field, including Karl Frederick Poetter and Paul Charles Mulvaney. These collaborations have further enriched his work and expanded the impact of his inventions.
Conclusion
Brendan Toohey is a prominent inventor whose work in biosensor technology has led to significant advancements in the detection of target analytes. His innovative patents and collaborations highlight his contributions to the field, making him a key figure in the realm of molecular biology.