Brandon J Rice

Title: Innovations by Brandon J Rice

Introduction

Brandon J Rice is an accomplished inventor based in Santa Cruz, CA. He has made significant contributions to the field of genomics, holding a total of 6 patents. His work focuses on innovative methods for nucleic acid assembly and preservation, which are crucial for advancements in genetic research.

Latest Patents

One of his latest patents is titled "Tagging nucleic acids for sequence assembly." This invention discloses various approaches for generating long-distance contiguity information to facilitate contig assembly and phase determination. Nucleic acids are assembled into complexes using binding moieties, ensuring that when the nucleic acid backbones are cleaved, the ensuing fragments remain bound. Exposed ends are tagged and ligated either to one another or to tagging moieties such as oligo labels. The ligated junctions are sequenced, and the sequence information is utilized to assemble contigs into common scaffolds or to assign phase information. Various approaches to tagging the exposed ends are presented in this patent.

Another notable patent is "Physical linkage preservation in DNA storage." This invention relates to compositions, systems, kits, and methods for preserving physical linkage information of isolated DNA subject to damage. It identifies a nucleic acid preservative that helps maintain DNA integrity. The methods involve reassembly of chromatin onto isolated DNA molecules to protect the nucleic acids and preserve physical linkage information. The nucleic acid compositions produced by these methods are preserved for analysis, such as high-throughput sequencing.

Career Highlights

Brandon J Rice is currently employed at Dovetail Genomics, LLC, where he continues to innovate in the field of genomics. His work has been instrumental in developing new techniques that enhance the understanding of genetic material.

Collaborations

He collaborates with notable colleagues, including Nicholas H Putnam and Jonathan Stites, who contribute to his research endeavors.

Conclusion

Brandon J Rice's contributions to the field of genomics through his innovative patents are paving the way for advancements in genetic research and applications. His work exemplifies the importance of innovation in the scientific community.