Location History:
- Canterbury, EN (1977 - 1978)
- Canterbury, GB (1979 - 1980)
Company Filing History:
Years Active: 1977-1980
Title: Braham Shroot: Innovator in Antibacterial Agents
Introduction
Braham Shroot is a distinguished inventor based in Canterbury, GB. He has made significant contributions to the field of medicinal chemistry, particularly in the development of novel antibacterial agents. With a total of 8 patents to his name, Shroot's work has had a profound impact on the treatment of bacterial infections.
Latest Patents
Among his latest patents, Shroot has developed a series of novel 7-(D-.alpha.-acylaminoarylacetamido)-.DELTA..sup.3 -cephem derivatives. These compounds feature an acyl moiety containing an epoxy group adjacent to the carbonyl carbon atom. They are particularly useful as antibacterial agents for treating diseases caused by both Gram-negative and Gram-positive bacteria. Notable examples include 7-[D-.alpha.-(cis-2-carboxyoxiran-3-carboxamido)phenylacetamido]-3-(1-methyl-1,2,3,4-tetrazol-5-ylthiomethyl)-.DELTA..sup.3 -cephem-4-carboxylic acid and 7-[D-.alpha.-(cis-2-carboxyoxiran-3-carboxamido)phenylacetamido]cephalosporanic acid. Additionally, he has created a series of novel 7-(D-.alpha.-aminophenylacetamido)- and 7-(D-.alpha.-hydroxyphenylacetamido)-.DELTA..sup.3 -cephem derivatives, which also serve as effective antibacterial agents.
Career Highlights
Braham Shroot is currently associated with Pfizer Corporation, a leading global pharmaceutical company. His work at Pfizer has allowed him to focus on innovative solutions for combating bacterial infections. His research has led to the development of compounds that are crucial in the fight against antibiotic resistance.
Collaborations
Shroot has collaborated with notable colleagues in his field, including Barry C. Ross and Charles A. Baxter. These collaborations have further enhanced the scope and impact of his research.
Conclusion
Braham Shroot's contributions to the field of antibacterial agents are invaluable. His innovative patents and collaborations with esteemed colleagues underscore his commitment to advancing medical science. His work continues to play a critical role in addressing the challenges
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