This inventor holds 3 USPTO granted patents and 1 published patent application. Top assignee: Duke University. Active years: 2004-2010.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2004-2010
Title: Innovations of Bradley Lowell Hodges
Introduction
Bradley Lowell Hodges is a notable inventor based in Milford, MA (US). He has made significant contributions to the field of biotechnology, particularly in the development of adenovirus vectors. With a total of 3 patents to his name, Hodges continues to push the boundaries of scientific research and innovation.
Latest Patents
Hodges' latest patents include groundbreaking work on deleted adenovirus vectors and methods of making and administering them. The invention provides deleted adenovirus vectors that carry one or more deletions in the IVa2, 100K, polymerase, and/or preterminal protein sequences of the adenovirus genome. These adenoviruses are designed to be 'propagation-defective', meaning they cannot replicate and produce new virions without complementing functions. The vectors are particularly useful for delivering heterologous nucleotide sequences encoding proteins associated with metabolic disorders, such as lysosomal or glycogen storage diseases.
Another significant patent involves replicating adenovirus vectors that have an impairment in 100K activity. This impairment is achieved through a deletion in the 100K coding region of the adenovirus vector genome. The invention also describes methods for making and administering these adenovirus vectors to cells or subjects, showcasing Hodges' commitment to advancing therapeutic applications.
Career Highlights
Hodges is affiliated with Duke University, where he conducts research and collaborates with other experts in the field. His work has garnered attention for its potential to address complex medical challenges through innovative viral vector technologies.
Collaborations
Hodges has worked alongside esteemed colleagues such as Andrea Amalfitano and Yuan Tsong Chen. Their collaborative efforts contribute to the advancement of research in adenoviral therapies and vector development.
Conclusion
Bradley Lowell Hodges exemplifies the spirit of innovation in biotechnology through his patents and research at Duke University. His work on adenovirus vectors holds promise for future medical advancements and therapeutic solutions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile