Company Filing History:
Years Active: 2009
Title: Bohumil Proksa: Innovator in Pharmaceutical Chemistry
Introduction
Bohumil Proksa is a notable inventor based in Hlohovec, Slovakia. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of methods for synthesizing important medicinal compounds. With a total of 2 patents, his work has had a meaningful impact on the pharmaceutical industry.
Latest Patents
Proksa's latest patents include a method for the preparation of oxycodone and a process for the preparation of carvedilol. The method of preparation of oxycodone involves reacting thebaine or its analogues with hydrogen peroxide or peroxoacids in the presence of oxalic acid and acetic or formic acid. This process results in the formation of 14-hydroxycodeinone, which is then hydrogenated to yield oxycodone, an active ingredient in analgesic formulations. His second patent details a new method for synthesizing carvedilol, which is achieved through a reaction involving 4-(oxirane-2-ylmethoxy)-9H-arbazole and 2-(2-methoxyphenoxy)ethylamine salts in an alcohol solvent at elevated temperatures. The crude product is purified through crystallization to obtain the final substance.
Career Highlights
Bohumil Proksa has been associated with Zentiva, a prominent pharmaceutical company, where he has applied his expertise in drug synthesis. His innovative approaches have contributed to the development of effective pharmaceutical products, enhancing the company's portfolio.
Collaborations
Proksa has collaborated with notable colleagues, including Vladislav Snuparek and Lubica Ratkovska. Their combined efforts in research and development have fostered advancements in pharmaceutical chemistry.
Conclusion
Bohumil Proksa's contributions to the field of pharmaceutical chemistry through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of essential medicinal compounds.