Bing Hao Luo

Title: Bing Hao Luo: Innovator in Integrin Research

Introduction

Bing Hao Luo is a notable inventor based in Baton Rouge, LA (US). He has made significant contributions to the field of drug discovery through his innovative research on integrins. His work focuses on stabilizing integrins in a closed state, which has important implications for therapeutic treatments.

Latest Patents

Bing Hao Luo holds a patent titled "Stabilized low affinity conformation of integrins for drug discovery." This patent describes methods and compositions that leverage the introduction of a disulfide bond into an integrin polypeptide. By substituting at least one cysteine residue in the polypeptide, Luo's approach stabilizes the integrin in a 'closed/inactive' state. This stabilization allows for the screening of candidate molecules that can bind to the closed state, which is crucial for developing agents that prevent integrin activation.

Career Highlights

Luo is associated with the Children's Medical Center Corporation, where he applies his expertise in integrin research. His work is pivotal in advancing the understanding of integrin functions and their role in drug discovery.

Collaborations

Luo collaborates with Timothy Alan Springer, a fellow researcher in the field. Their partnership enhances the potential for innovative breakthroughs in integrin-related therapies.

Conclusion

Bing Hao Luo's contributions to integrin research and drug discovery exemplify the impact of innovative thinking in the medical field. His patent and ongoing work continue to pave the way for new therapeutic approaches.