Bin Sun

Title: Innovations by Bin Sun in Surface Plasmon Resonance Technology

Introduction

Bin Sun is an accomplished inventor based in Falls Church, VA (US). He has made significant contributions to the field of biomolecular analysis through his innovative work on surface plasmon resonance compatible carbon thin films. His research focuses on enhancing the capabilities of microarray fabrication and analyses.

Latest Patents

Bin Sun holds a patent for "Surface plasmon resonance compatible carbon thin films." This patent describes SPR-compatible substrates that facilitate high-density microarray fabrication and analyses. The novel carbon-on-metal thin film substrate architecture allows for the integration of surface plasmon resonance detection with photolithographically fabricated biomolecule arrays. This technology is instrumental in analyzing biomolecular interactions, including specific DNA-DNA, DNA-RNA, and DNA-protein binding interactions. The substrates developed by Sun can also be utilized to determine the secondary structure of RNA molecules and probe the sequence-specific binding kinetics and affinity of proteins and small molecules. Additionally, they serve as substrates for small-molecule combinatorial chemistry platforms, which are vital for drug discovery applications.

Career Highlights

Bin Sun is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in various fields, including biotechnology and pharmaceuticals.

Collaborations

He has collaborated with notable colleagues, including Lloyd M. Smith and Matthew R. Lockett, who have contributed to his research endeavors.

Conclusion

Bin Sun's innovative work in surface plasmon resonance technology has the potential to revolutionize biomolecular analysis and drug discovery. His contributions are paving the way for advancements in understanding biomolecular interactions and developing new therapeutic strategies.