Biao Liu

Title: Biao Liu - Innovator in Triptolide Derivatives

Introduction

Biao Liu is a prominent inventor based in Hong Kong, CN. He has made significant contributions to the field of medicinal chemistry, particularly in the development of triptolide derivatives. His innovative work focuses on enhancing the therapeutic potential of these compounds.

Latest Patents

Biao Liu holds a patent for "Triptolide derivatives and preparation method and use thereof." This patent details the creation of triptolide-nucleic acid aptamer derivatives, which are designed to improve targeting and efficacy in cancer treatment. The invention utilizes a nucleic acid aptamer and triptolide or its modified compounds as starting materials. A linking group is introduced at the C-14 hydroxyl group, epoxy groups, and five-membered ring lactones in triptolide, resulting in derivatives that exhibit good targeting, high anti-cancer activity, low toxicity, and excellent water solubility. The preparation method is noted for its scientific rigor, controllable quality, and good repeatability, making it suitable for production.

Career Highlights

Biao Liu is affiliated with Hong Kong Baptist University, where he conducts research and develops innovative solutions in the field of pharmaceuticals. His work has garnered attention for its potential impact on cancer therapies.

Collaborations

Biao Liu collaborates with notable colleagues, including Ge Zhang and Aiping Lu, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Biao Liu's contributions to the field of triptolide derivatives highlight his role as an influential inventor in medicinal chemistry. His innovative approaches promise to advance cancer treatment methodologies significantly.