Location History:
- New York, NY (US) (1997 - 2001)
- Palisades Park, NJ (US) (2003)
Company Filing History:
Years Active: 1997-2003
Title: Bi-Xing Chen: Innovator in Antibody Research
Introduction
Bi-Xing Chen is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of antibody research, holding a total of 6 patents. His work focuses on innovative methods and applications that have the potential to impact medical science.
Latest Patents
One of Bi-Xing Chen's latest patents involves the development of antibodies specific for fullerenes. This invention provides a hybridoma produced by the fusion of a mouse antibody-producing cell and a mouse myeloma, designated 1-10F-8A. This hybridoma produces a monoclonal antibody that binds to fullerene C60. The invention also includes the amino acid and encoding nucleic acid sequences of the heavy and light chains of the 1-10F-8A monoclonal antibody. Additionally, it offers methods for determining serum concentrations of fullerenes in subjects and purifying fullerenes from samples.
Another significant patent focuses on screening methods for identifying anti-HIV compounds using a cyclosporine-specific monoclonal antibody that cross-reacts with HIV-1 p24. This invention provides new uses for novel derivatives of cyclosporine A and antibodies directed toward them. The derivatives and antibodies are useful in treating AIDS, purifying the Gag protein of HIV, screening for anti-HIV compounds, and detecting HIV in subjects. These innovations can also be incorporated into kits for screening anti-HIV compounds.
Career Highlights
Bi-Xing Chen is affiliated with Columbia University, where he continues to advance his research in antibody development and applications. His work has garnered attention in the scientific community for its potential to address critical health challenges.
Collaborations
Bi-Xing Chen has collaborated with notable colleagues, including Bernard F Erlanger and Jyh-Gang Leu. These partnerships have contributed to the advancement of his research and the development of innovative solutions in the field.
Conclusion
Bi-Xing Chen is a distinguished inventor whose work in antibody research has led to significant advancements in medical science. His innovative patents and collaborations highlight his commitment to addressing pressing health issues through scientific discovery.