Title: Bhaskara R Jasti: Innovator in Liposomal Nanoparticle Formulations
Introduction
Bhaskara R Jasti is an accomplished inventor based in Stockton, CA (US). He has made significant contributions to the field of drug delivery systems, particularly through his innovative work on liposomal nanoparticles. His research focuses on enhancing the therapeutic efficacy of retinoids, specifically fenretinide.
Latest Patents
Bhaskara R Jasti holds a patent titled "Liposomal Nanoparticles And Other Formulations Of Fenretinide For Use In Therapy And Drug Delivery." This patent describes formulations of neutral retinoids, particularly fenretinide (HPR), in the form of lipid nanoparticles, solid dispersions, and emulsions. These compositions are designed to treat diseases that can be addressed by HPR, such as neoplastic diseases, by achieving higher and more prolonged concentrations of HPR in the subject. The key steps for preparing lipid nanovesicles of HPR include mixing and sonication, sterile filtration, and optional lyophilization for long-term stable storage. The formulations are suitable for injection into human or animal patients without causing allergic or hypersensitivity responses, as they avoid chemical surfactants and animal sources of phospholipids in their manufacture.
Career Highlights
Throughout his career, Bhaskara R Jasti has worked with notable institutions, including Wayne State University and Scitech Development, LLC. His work has focused on developing innovative drug delivery systems that enhance the therapeutic potential of various compounds.
Collaborations
Some of his notable coworkers include Ralph E Parchment and Ramesh R Boinpally. Their collaborative efforts have contributed to advancements in the field of drug delivery and therapeutic formulations.
Conclusion
Bhaskara R Jasti's work in liposomal nanoparticles and drug delivery systems represents a significant advancement in therapeutic applications. His innovative formulations have the potential to improve treatment outcomes for various diseases.