Beverley Moore

Title: Beverley Moore: Innovator in Matrix Metalloproteinase Inhibition

Introduction

Beverley Moore is a distinguished inventor based in North Wales, PA (US). She has made significant contributions to the field of biochemistry, particularly in the development of methods for treating diseases related to matrix metalloproteinase (MMP) activity. Her innovative work has led to the granting of a patent that showcases her expertise and dedication to advancing medical treatments.

Latest Patents

Beverley Moore holds a patent for "Methods of treatment using allosteric processing inhibitors for matrix metalloproteinases." This invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits the activation of the proMMP. The patent outlines methods for identifying these inhibitors and their application in treating diseases mediated by inappropriate MMP activity. The invention further details the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor, providing valuable insights for designing and optimizing such inhibitors.

Career Highlights

Beverley Moore has established herself as a key figure in her field through her innovative research and development efforts. Her work at Janssen Pharmaceutica NV has allowed her to collaborate with other experts and contribute to groundbreaking advancements in medical science.

Collaborations

Beverley has worked alongside notable colleagues, including Kristi A Leonard and Richard Scott Alexander. These collaborations have enhanced her research and expanded the impact of her inventions in the scientific community.

Conclusion

Beverley Moore's contributions to the field of matrix metalloproteinase inhibition exemplify her commitment to innovation and medical advancement. Her patent and collaborative efforts reflect her significant role in developing treatments for diseases associated with MMP activity.