Bert Willis

Title: Bert Willis: Innovator in Nicotine Synthesis

Introduction

Bert Willis is a notable inventor based in Mills River, North Carolina. He has made significant contributions to the field of chemistry, particularly in the synthesis and resolution of nicotine. With a total of three patents to his name, Willis continues to push the boundaries of innovation in his area of expertise.

Latest Patents

One of Bert Willis's latest patents focuses on the synthesis and resolution of nicotine. This patent outlines methods for preparing nicotine and resolving R,S nicotine to enrich the (S)(−) enantiomer. The process involves combining N-methyl-2-pyrrolidone or a salt thereof with a nicotinate compound in the presence of a solvent and a strong base. This combination forms 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof. The subsequent reduction of this compound in solution with NaSO produces racemic nicotine or its salt. The resolution of racemic nicotine may involve combining it with (−)-O,O'-di-p-toluoyl-L-tartaric acid (L-PTTA).

Career Highlights

Bert Willis has established himself as a key figure in the field of nicotine research. His innovative methods have the potential to enhance the production and application of nicotine in various industries. Working at Njoy, Inc., he has contributed to the development of products