Bernhard M Schilling

Title: Innovations in Protein Production by Bernhard M Schilling

Introduction

Bernhard M Schilling is a notable inventor based in Syracuse, NY (US). He has made significant contributions to the field of protein production through his innovative methods and processes. With a total of 2 patents, Schilling's work focuses on enhancing the quality and yield of proteins, particularly glycoproteins, through advanced cell culture techniques.

Latest Patents

Schilling's latest patents include groundbreaking inventions in mammalian cell culture processes for protein production. The first patent describes methods for producing proteins by animal or mammalian cell culture, emphasizing the importance of temperature shifts during the culturing period. These shifts help maintain high cell viability and improve the quality of the protein product. The second patent outlines methods for enhancing product quality by feeding cells with D-galactose, which sustains effective levels of sialylation in the culture. This approach not only increases the sialylation of produced proteins but also allows for an extended protein production phase.

Career Highlights

Bernhard M Schilling is currently associated with Bristol-Myers Squibb Company, where he applies his expertise in protein production. His innovative approaches have the potential to revolutionize the biopharmaceutical industry by improving the efficiency and quality of protein-based therapies.

Collaborations

Schilling has collaborated with notable colleagues, including Linda Matlock and Stephen G Zegarelli. These partnerships have contributed to the advancement of his research and the successful implementation of his patented methods.

Conclusion

Bernhard M Schilling's contributions to protein production through innovative cell culture processes highlight his role as a leading inventor in the field. His patents not only enhance the quality of glycoproteins but also pave the way for advancements in biopharmaceutical manufacturing.