This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignee: Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.v.. Active years: 2020.
Company Filing History:
Years Active: 2020
Title: The Innovations of Bernhard Brune
Introduction
Bernhard Brune is a notable inventor based in Schoeneck, Germany. He has made significant contributions to the field of immunology through his innovative research and patents. His work focuses on the development of therapeutic proteins that can potentially address autoimmune disorders.
Latest Patents
Bernhard Brune holds a patent for an invention titled "N-terminally truncated interleukin-38." This invention pertains to an N-terminally truncated interleukin (IL)-38 protein, or functional variants thereof, as well as to nucleic acids and vectors encoding the truncated IL-38 peptide and recombinant cells comprising these nucleic acids or vectors. The invention demonstrates that IL-38 is N-terminally processed and that the truncated version of the cytokine acts as an antagonist of immune activation in macrophages. This indicates a potential use of the truncated cytokine in the treatment and prevention of autoimmune disorders. The invention further provides pharmaceutical compositions comprising the truncated IL-38 protein and methods for screening modulators of the function of truncated IL-38.
Career Highlights
Bernhard Brune is associated with the Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., a leading research organization in Germany. His work at this institution has allowed him to collaborate with other experts in the field and contribute to groundbreaking research.
Collaborations
Some of his notable coworkers include Christina Dillmann and Andreas Weigert. Their collaborative efforts have further advanced the research and development of innovative solutions in immunology.
Conclusion
Bernhard Brune's contributions to the field of immunology through his patent on N-terminally truncated interleukin-38 highlight his role as an influential inventor. His work has the potential to impact the treatment of autoimmune disorders significantly.